This summary of Arthrosamid for knee OA aims to inform and empower anyone considering this treatment option. The decision to proceed with any medical treatment should always be made in consultation with our Clinical Lead, Gill Coates, to ensure it aligns with your individual needs and circumstances.

ARTHROSAMID

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What Is Arthrosamid and How Does It Work?

Arthrosamid® is an injectable, clear, hydrophilic gel that is both non-absorbable and non-biodegradable. It is composed of a solid framework of non-biodegradable polyacrylamide (2.5%) intertwined with non-pyrogenic water (97.5%).

This product is provided in six sterile, pre-filled syringes designed for single use, containing 1 mL of the gel in each syringe. This hydrogel acts as a cushion inside the joint and is designed to integrate with the tissue within the knee, providing support and reducing pain without degrading over time. The unique properties of Arthrosamid® allow it to offer both immediate and sustained relief from Osteoarthritis (OA) symptoms, making it an attractive option for those seeking alternatives to traditional therapies.

Arthrosamid might be ideal for you if:

  • You've already tried steroid or hyaluronic acid injections without lasting relief

  • You're looking for a solution to avoid or delay knee replacement surgery

  • You want long-term pain relief with a single injection

  • You prefer a treatment that doesn't require repeated appointments

  • You're active and want to stay mobile without downtime

  • You value precision and safety with ultrasound-guided care by an experienced clinician

What can I expect at Physio Edge?

The injection procedure is minimally invasive and typically conducted in an outpatient setting by an experienced clinician. It involves an ultrasound guided injection of Arthrosamid® directly into the intra-articular space of the knee. The procedure is quick, does not require hospitalisation, and patients can usually resume normal activities shortly afterward. The simplicity and safety of the procedure make it an appealing option for many patients.

Benefits and Efficacy

Arthrosamid® has been shown to provide significant pain relief within four weeks post-injection, with the effects sustained over a period of 156 weeks in clinical trials. This long-term relief is a key advantage of Arthrosamid® over other injectable treatments for OA, which may require more frequent administration. The hydrogel's safety and efficacy are supported by over two decades of research and development, along with clinical trials that document its positive impact on patients' pain levels and mobility.

  • Long-lasting pain relief

  • Reduced stiffness and improved mobility

  • Decreased need for pain medications or repeated injections

  • Improved quality of life for those with moderate knee OA

Safety and Considerations

As with any medical procedure, there are potential risks and considerations associated with Arthrosamid® injections. However, the hydrogel has been extensively tested for biocompatibility and safety, with a very low incidence of adverse effects reported. It is crucial for patients to discuss their individual medical history and potential risks with their healthcare provider before proceeding with the treatment.

  • Minimal side effects reported in trials

  • Does not degrade over time, reducing risk of re-injection complications

  • No known systemic effects

Possible Side Effects:

  • Mild swelling or discomfort at the injection site (temporary)

  • Very rare: joint stiffness or a local inflammatory reaction

Who Should Avoid Arthrosamid?

  • Patients with an active joint inflammation, Rheumatoid Arthritis, Gout and Psoriatic Arthritis.

  • Patients allergic to any component of the hydrogel (rare)

Arthrosamid® offers a promising new avenue for managing knee osteoarthritis, providing a safe, effective, and long-lasting alternative to traditional treatments.

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